HBeAg positive patients older than years with persistently

2019-04-15

HBeAg-positive patients older than 40 years with persistently high or high to normal ALT levels may be diagnosed with significant hepatic necroinflammation or fibrosis. During treatment, the clinical significance of timing of HBeAg loss or seroconversion remains unclear. However, a longer duration o

br Methods br Discussion This study demonstrated

2019-04-15

Methods Discussion This study demonstrated that upgrading to CRT from RVAP improved cardiac performance and myocardial perfusion at pacing sites by SPECT. RVAP has been reported to alter left ventricular electrical and mechanical activation in a manner that is similar to the complete left bund

br How do you manage patients

2019-04-15

How do you manage patients on intravenous bone-targeted agents who require dental work? For patients who are on IV bisphosphonate therapy and require dento-alveolar procedures there is a suggestion that prophylactic antibiotic use around the procedure may be helpful in reducing ONJ risk [45,49].

br Conclusion br Conflict of interest This work

2019-04-15

Conclusion Conflict of interest This work was supported by Medtronic Japan. MN received honoraria from Medtronic Japan, St. Jude Medical Japan and Boston Scientific Japan. YE and TI received honoraria from Medtronic Japan. HS received honoraria from Japan Lifeline. YA, TT, and KK are employee

The most compelling apparent evidence in

2019-04-15

The most compelling apparent evidence in support of the depolarization hypothesis derives from the seminal studies of Nademanee et al. [129]. showing that radiofrequency ablation (RFA) of epicardial sites displaying late potentials and fractionated bipolar electrograms in the RVOT of patients with B

igf 1 inhibitor When compared with lidocaine both amiodarone

2019-04-15

When compared with lidocaine, both amiodarone and nifekalant were proved similarly effective for ventricular arrhythmias suppression. These drugs, however, have characteristic adverse effects, such as negative inotropic and chronotropic outcomes (amiodarone), and QT prolongation resulting in torsade

br Therapy for the CPVT br

2019-04-15

Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele

buy LKB1 The so called driver hypothesis has been posited in

2019-04-15

The so-called driver buy LKB1 has been posited in the recent years. Optical mapping studies in isolated sheep hearts have suggested that at least some cases of AF can be maintained by high-frequency reentrant sources (rotors), usually located in the posterior LA, which result in spatially distribut

We would like to also clarify that

2019-04-11

We would like to also clarify that we do not underestimate the CIs in our study through the assumption that GDP was observed independently for every child in the survey. The multilevel design and clustering of standard errors at the survey level accounts for the fact that GDP is not observed indepen

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2018-07-29