• br Voltage dependent anion channel VDAC is

  2022-02-14

  

  Voltage-dependent anion channel VDAC is a ubiquitous protein showing well conserved structural and functional properties in spite of major variations in its sequence (for review see [50]). Most of what we know about VDAC electrophysiological properties (for reviews, see [51], [52]) was initially

• br Funding Our work in

  2022-02-14

  

  Funding Our work in this field was supported by CNRSLIA528, Agence Nationale de la Recherche 06-Neuro, Agence Nationale de la Recherche MNMP 2009. Introduction GABA and the GI motility The role of GABA in the modulation of GI motility is quite complex and not fully understood, since GABA-i

• br Role of FPRs in regulating the inflammatory response Anne

  2022-02-14

  

  Role of FPRs in regulating the inflammatory response Annexin I is a glucocorticoid-regulated protein possessing both pro- and anti-inflammatory activity that might be mediated, in part, by FPR activation [35]. Expressed in a variety of cell types, annexin I is particularly abundant in neutrophils

• Apicidin Receptor activator of NF B ligand RANKL and macroph

  2022-02-14

  

  Receptor activator of NF-κB ligand (RANKL) and macrophage colony-stimulating factor (M-CSF) stimulate the generation of osteoclast Apicidin [10], [11], [12], [13]. In response to sphingosine 1-phosphate (S1P) signaling, osteoclasts then attach to regions of bone undergoing resorption [14]. In RA wh

• This study appears to provide

  2022-02-12

  

  This study appears to provide an additional example, albeit an unanticipated one, of the importance of renal ETB receptor function in the normal control of blood pressure and salt and water homeostasis. ETB receptor-deficient rats, collecting duct-specific ETB receptor knockout mice, and rats chroni

• br Funding The research for this

  2022-02-12

  

  Funding The research for this paper is conducted as part of a PhD thesis at Pasteur Institute of Iran and it was financially supported by Pasteur Institute of Iran and the Iranian Centre for Communicable Diseases. Conflict of interest Acknowledgments Introduction The viral enzyme integr

• br Conclusion The following is

  2022-02-12

  

  Conclusion The following is the supplementary data related to this article. Conflict of interest Author contributions Heart transplantation is the most important treatment for end-stage heart failure. Ischemia/reperfusion injury is a common condition during transplantation surgery and is

• N1-Methylpseudouridine We started our investigation by evalu

  2022-02-12

  

  We started our investigation by evaluating the impact of changes to the piperidine moiety of (). As demonstrated with morpholine and piperazine , attenuation of nitrogen basicity resulted in complete loss of activity, suggesting that a basic heterocyclic nitrogen is important for potent inhibition

• br Introduction Verticillium dahliae Kleb is a soil borne

  2022-02-12

  

  Introduction Verticillium dahliae (Kleb.) is a soil-borne fungal pathogen that is able to infect hundreds of plant species, and causes vascular wilt disease [1], [2]. In nature, the infection of V. dahliae initiates from the germination of resting structures called microsclerotia [3]. The germina

• br Experimental br Results and discussions br Conclusions

  2022-02-12

  

  Experimental Results and discussions Conclusions In this work, a novel label-free ECL biosensing method was developed to detect TDG activity using signal amplification strategy of HCR which was triggered by DNA functionalized AuNPs. The label-free ECL biosensing platform has been constructe

• br Materials and methods br

  2022-02-12

  

  Materials and methods Results Discussion Acknowledgments This work was financially supported by the University of Tehran, Iran. The authors thank all the teams who worked on the experiments and who provided technical assistance in the laboratory during this study. We also thank the anony

• The effects of galanin on anxiety may depend on

  2022-02-12

  

  The effects of galanin on anxiety may depend on the site of drug administration, on the galanin receptor subtypes activated and on the animal models of anxiety employed (Barrera et al., 2005, Holmes and Picciotto, 2006, Soares et al., 2016a, Soares et al., 2016b). For instance, administration of gal

• In addition to the type of food consumed also

  2022-02-12

  

  In addition to the type of food consumed, also the effect of calorie restriction (CR), i.e. an intermittent fasting and re-feeding cycles with concomitant fluctuations in the level of glucose and insulin, can affect the course of IBS through the modulation of the BA homeostasis. This type of nutriti

• nsc library receptor Type II diabetes is characterized by an

  2022-02-11

  

  Type II diabetes is characterized by an inability to maintain glucose homeostasis due to insulin desensitization and/or insufficient insulin secretion. GPR40, also known as free fatty nsc library receptor receptor 1 (FFAR1), is a member of the G-protein-coupled lipid-activated family of receptors a

• br Conclusion br Funding br

  2022-02-11

  

  Conclusion Funding Availability of data and materials Authors' contributions Ethics approval and consent to participate Consent for publication Competing interests Introduction Hepatitis C virus (HCV) infection is a global public health problem. An estimated 71.1 million peop

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